Lipetz worked at: Brookhaven Lab, Upton, NY 1948-50; Research associate, History of Science Department, Cornell 1951-52; Research assistant, Lab of Nuclear Studies, 1952; Assistant chief, Information Management Division, Battelle 1953-59; Head, Systems Applications Section, Itek Corporation 1959-62; Counsul on Information Management and Research, Carlisle Mass. 1962-66; Head Research Department, Yale Library 1966-?; Editor of Information Science Abstracts. He was a professor at SUNY-Albany.

He developed the concept of continuity index based on citation indexing but added a code to indicate by code the reason why a reference had been made. Lipetz was engaged in major study of catalog use in 1960s. He published a work on the nature of scientific discoveries.